Electrocardiographic changes in healthy and preeclamptic pregnant women

Maryam Zangeneh, Firoozeh Veisi, Shohreh Malekkhosravi, Negin Rezavand, Anisodoleh Nankali, Mansour Rezaei, Mohammad Rasoul Ghadami, Amid Karami

Abstract


Background: Preeclampsia is a condition observed during pregnancy and threatens the life of both mother and fetus. There are studies which suggest that preeclampsia play a major role in the left ventricular mass. The aim of this study is to compare the electrocardiographic changes in normal pregnant and preeclamptic women.

Methods: The studied groups consisted of 48 mild preeclamptic, 33 severe preeclamptic and 42 normal pregnant women. To measure left ventricular indices such as Sokolow and Cornell; the obtained ECGs from patients were used.

Results: The left ventricular mass in preeclamptic group, severely preeclamptic group and control group were 21.62mm, 23.45mm, and 20.85mm respectively. There was no statistically significant difference among groups with regards to Sokolow index. The left ventricular mass in preeclamptic group, severely preeclamptic group and control group were 10.52mm, 12.30mm, 9.07mm. There were statistically significant differences among the groups with regards to Cornell index.

Conclusion: It seems that the increasing of left ventricular mass is one of the important effects in preeclampsia during pregnancy whose recognition has been done in previous studies via ECG. The Results of this study showed that electrocardiography could be used as an instrument in the diagnosis of left ventricular function in preeclamptic women.


References


Haider AW, Larson MG, Benjamin EJ, Levy D. Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death. J AmColl Cardiol. 1998; 32:1454-9.

Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Gattobigio R, Zampi I. Prognostic value of a new electrocardiographic method for diagnosis of left ventricular hypertrophy in essential hypertension. J Am Coll Cardiol. 1998; 31:383-90.

Sundström J, Lind L, Arnlöv J, Zethelius B, Andrén B, Lithell HO. Echocardiographic and electrocardiographic diagnoses of left ventricular hypertrophy predictmortality independently of each other in a population of elderly men. Circulation. 2001; 103:2346-51.

Dunn FG, McLenachan J, Isles CG, Brown I, Dargie HJ, Lever AF. Left ventricular hypertrophy and mortality in hypertension: an analysis of data from the Glasgow Blood Pressure Clinic. J Hypertens. 1990; 8:775-82.

Sever PS, Dahlof B, Poulter NR, Wedel H, Beevers G, Caulfield M. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian cardiac outcomes trial-lipid lowering arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet. 2003; 361:1149-58.

Williams B, Poulter NR, Brown MJ, Davis M, McInnes GT, Potter JF. British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary. BMJ. 2004; 328:634-40.

Pewsner D, Jüni P, Egger M, Battaglia M, Sundström J, Bachmann LM. Accuracy of electrocardiography in diagnosis of left ventricular hypertrophy in arterial hypertension: systematic review BMJ. 2007; 335; 711.

Vakili BA, Okin PM, Devereux RB. Prognostic implications of left ventricular hypertrophy. Am Heart J. 2001; 141:334-41.

Lonn E, Mathew J, Pogue J, Johnstone D, Danisa K, Bosch J. Relationship of electrocardiographic left ventricular hypertrophy to mortality and cardiovascular morbidity in high-risk patients. Eur J Cardiovasc Prev Rehabil. 2003; 10:420– 8.

Okin PM, Devereux RB, Jern S, Kjeldsen SE, Julius S, Nieminen MS, et al. Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events. JAMA. 2004; 292(19):2343-9.

Visser W, Wallenburg HC. Central hemodynamic observations in untreated preeclamptic patients. Hypertension. 1991; 17:1072–1077.

Dennis LK, Braunwald E, Hauser S, Longo D, Jameson JL, Fauci AS. Harrison's Principles of Internal Medicine 16th Edition.

Ghali JK, Liao Y, Simmons B, Castaner A, Cao G, Cooper RS. The prognostic role of left ventricular hypertrophy in patients with or without coronary artery disease. Ann Intern Med. 1992;117: 831-6.

Simmons LA, Gillin AG, Jeremy RW. Structural and functional changes in left ventricle during normotensive and preeclamptic pregnancy. Am J Pheart.physiology. 2002; 283:627-33.

De Conti F, Da Corta R, Del Monte D, Catena V, Berton G, Mormino P, et al. Left ventricular diastolic function in pregnancy-induced hypertension. Ital Heart J. 2003; 4(4): 246-51.

Hoogsteder PH, Kruse AJ, Sep SJ, Dassen WR, Gorgels AP, Peeters LL. Electrocardiographic findings in women with a recent history of preeclampsia: ECG findings in preeclampsia. Acta Obstet Gynecol Scand. 2012;91(3):372-8.

Borghi C, Esposti DD, Immordino V, Cassani A, Boschi S, Bovicelli L, et al. Relationship of systemic hemodynamics, left ventricular structure and function, and plasma natriuretic peptide concentrations during pregnancy complicated by preeclampsia. Am J Obstet Gynecol. 2000; 183(1): 140-7.

Vasapollo B, Novelli G P, Valensise H. Total vascular resistance and left ventricular Morphology as Screening Tools for Complications in Pregnancy. Hypertension. 2008; 51(4): 1020-6.

González-Juanatey JR, Cea-Calvo L, Bertomeu V, Aznar J; for Investigators study VIIDA. [Electrocardiographic criteria for left ventricular hypertrophy and cardiovascular risk in hypertensives. VIIDA study (Spanish)]. Rev Esp Cardiol. 2007; 60(2): 148-56.




DOI: http://dx.doi.org/10.22110/jkums.v16i4.674

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